Seeing is believing: How image-based profiling is revolutionizing the process of drug discovery While examining molded petri dishes after a vacation in 1928, Sir Alexander Fleming noticed that the periphery of the mold had no bacterial growth. He would come to find that the mold was secreting an antibacterial agent later called penicillin. This drug discovery revolutionized medicine.
Using Biodock to do science: PhD candidate's experience As a scientist who has collected and analyzed many images, I am well acquainted with the toil of manual analysis and the impressive potential utility Biodock has to offer. To instantiate this utility, I tried out Biodock myself.
Peering beyond the surface with Gradient Index lenses How do we look beyond the surface when imaging tissue? Today's article focuses on Gradient Index (GRIN) optics and how GRIN lenses are serving as a window into the deepest areas of the brain and body
Semantic vs. Instance Segmentation: Applications for Biology Consider a crowded room of your friends. In a snapshot of the image, semantic and instance segmentation models can be used to pick out people from the background. In the semantic model the output would be a silhouette of the whole group against the background.
Playing the brain's music back to itself with holographic optogenetics Chopin’s prelude No. 4 [https://www.youtube.com/watch?v=KHGHhYZCIQI] in E minor is widely venerated for its authentic musical depiction of despair. The haunting melody from gripping
Cheating the Diffraction Limit with Expansion Microscopy Imagine you are behind the camera framing a picture of your friend. Where you stand, you notice that although you are capturing much of the background, your friend is far
Carving out brain structure with connectomics Over two centuries ago Lewis and Clark embarked on an expedition to map the western United States. Charting landscapes and routes in between, their adventure into this unknown territory revolutionized